Vaccinating animals against Salmonella
Breeding animals often suffer from diarrhoea caused by Salmonella, but since the bacterium is constantly changing, previous vaccines quickly become ineffective. Wolf-?Dietrich Hardt, Emma Wetter Slack and Médéric Diard have developed a vaccine that exploits this genetic modification. Their vaccine triggers an immune response that directs the evolution of Salmonella in such a way that the only survivors are harmless pathogens that are also difficult to transmit to other animals.
Contact / Links:
Prof. Emma Slack, Laboratory for Food Immunology
Prof. Wolf-Dietrich Hardt, Institute of Microbiology
Publications:
patent pending (for further information contact )
“Tailored intestinal IgA responses can set an evolutionary trap for Salmonella Typhimurium”, Preprint available on request
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